What Is S4 SARM?
S4 SARM, also known as Andarine, is a selective androgen receptor modulator originally developed to treat muscle wasting and osteoporosis. Unlike anabolic steroids, S4 selectively binds to androgen receptors in muscle and bone tissue, which is why it became popular among bodybuilders during cutting phases.
S4 is mainly used to preserve lean muscle while reducing body fat, making it one of the most common SARMs for cutting and recomposition cycles.
What Does S4 SARM Do?

S4 SARM works by selectively activating androgen receptors in muscle tissue. This leads to:
- Increased muscle hardness
- Improved fat loss
- Better strength retention during calorie deficits
- Enhanced vascular appearance
Because it does not convert to estrogen, users do not experience estrogen-related side effects such as water retention or gynecomastia. LGD-4033 vs MK-2866: Which SARMs Is Better for Mass?
S4 SARM Uses in Bodybuilding
S4 is primarily used for:
- Cutting cycles
- Body recomposition
- Muscle preservation during fat loss
- Improving muscle definition
Many users report that S4 gives a “dry” and “grainy” look, which is why it is commonly used before competitions or photo shoots.
S4 Benefits
Lean Muscle Retention
S4 helps maintain muscle mass even when calories are low, which is one of its strongest benefits.
Fat Loss Support
By increasing metabolic activity and preserving muscle, S4 indirectly improves fat loss efficiency.
Increased Strength and Endurance
Users often notice improved workout performance and strength retention.
No Estrogen Conversion
S4 does not aromatize into estrogen, reducing the risk of estrogen-related side effects.
S4 SARM Dosage Guide
It has a short half-life, so split dosing is recommended.
| Experience Level | Daily Dosage |
|---|---|
| Beginner | 25 mg |
| Intermediate | 40–50 mg |
| Advanced | 60–75 mg |
Dosages are usually split into two doses per day to maintain stable blood levels.
S4 SARM Cycle Length
- Typical cycle length: 6–8 weeks
- Best used during a calorie deficit
- Not recommended to exceed 8 weeks due to side effects
S4 Results (Week-by-Week)

Weeks 1–2
Improved endurance, mild strength increase, and better muscle pumps.
Weeks 3–4
Visible fat loss, increased muscle hardness, enhanced vascularity.
Weeks 5–6
Maximum visual changes, dry and defined appearance, peak cutting results.
S4 Side Effects
Vision Issues (Most Discussed Side Effect)

S4 can bind to androgen receptors in the retina, causing:
- Yellow-tinted vision
- Difficulty adjusting to darkness
- Reduced night vision
This effect is dose-dependent and usually reversible after stopping use.
Testosterone Suppression
S4 can suppress natural testosterone production, especially at higher doses or longer cycles.
Other Possible Side Effects
- Mild headaches
- Fatigue
- Temporary lethargy
Does S4 SARM Cause Cancer?
There is no direct human evidence showing that S4 SARM causes cancer. However, since it is a research chemical with limited clinical data, long-term safety remains unknown. This is why S4 is not approved for human use.
Does S4 SARM Suppress Testosterone?
Yes, S4 can suppress testosterone, though usually less than stronger SARMs like RAD-140 or S23. Suppression depends on dosage, cycle length, and individual response.
S4 SARM PCT (Post Cycle Therapy)
- Mild cycles may recover naturally
- Moderate to high doses often require PCT
- Common PCT duration: 4 weeks
Natural testosterone support supplements are sometimes used after short cycles.
S4 SARM vs Ostarine

| Feature | S4 SARM | Ostarine |
|---|---|---|
| Best For | Cutting | Recomp / Beginners |
| Strength | Moderate | Mild |
| Suppression | Moderate | Low |
| Side Effects | Vision issues | Minimal |
S23 vs S4 SARM
| Feature | S4 SARM | S23 SARM |
|---|---|---|
| Strength | Moderate | Very High |
| Suppression | Moderate | Severe |
| Use Case | Cutting | Advanced cycles only |
| Safety | Moderate | High risk |
Common Confusion: S4 vs S42
Some users search for “S42,” which is often a mislabeling or confusion with S4 or S23. There is no widely recognized compound officially called S42 in mainstream SARM research. RAD-140 Testolone: Benefits, Dosage, Cycle, & Side Effects
Frequently Asked Questions
Is S4 SARM good for beginners?
It can be used by beginners, but vision side effects make Ostarine a safer first option.
Can women use S4?
Lower doses may be used, but the risk of side effects still exists.
Does S4 cause hair loss?
Hair loss is possible in genetically prone individuals.
Is S4 legal?
S4 is legal to purchase as a research chemical, but banned in professional sports.
WhatsApp Assistance Section
If you need guidance, cycle support, or help understanding SARMs, you can reach out directly on WhatsApp:
WhatsApp Support: https://wa.me/917696593279
For educational and research discussion only.
Conclusion
S4 is a powerful cutting compound known for muscle hardness, fat loss, and a dry physique. While effective, its vision-related side effects and testosterone suppression mean it should be used cautiously. For users seeking advanced cutting results and willing to manage side effects, S4 can be effective when used responsibly. SR9009 (Stenabolic): Benefits, Dosage & Results