Description
Denik Pharm INSUGRO-DS (IGF-1 DES) is a specially modified form of IGF-1, which plays a significant role in muscle growth and development.
| Contents | Vial: IGF1 DES (Somatomedin C), 1mg. Ampoule: Sterile water for injection 2ml. |
| Administration | Intramuscular or subcutaneous injection. |
| Storage | Store at room temperature away from heat and direct sunlight prior to reconstitution. Refrigerate between 2-8’C post reconstitution. |
| Dosage | Adult: SC IGF 1 deficiency Initial: 4 mcg/kg/day. May increase dose gradually. Max: 10 mcg/kg/day. HIV-associated wasting or cachexia 5 mcg/kg/day at bedtime. Can be administered multiples times a day. |
| Contraindications | Acute critical illness due to heart or abdominal surgery, multiple accidental trauma or respiratory failure; active neoplasms, proliferative or preproliferative diabetic retinopathy; lactation; patients with closed epiphyses. Intracranial lesions. Patients with Prader-Willi syndrome who are severely obese or have severe respiratory impairment. |
| Special Precautions | Monitor thyroid function; benign intracranial hypertension. DM; may require dose reduction in insulin. Pregnancy. Discontinue treatment if there is evidence of tumour growth. Monitoring in patients with scoliosis is recommended due to risk of progression of scoliosis. |
| Adverse Drug Reactions | Hypothyroidism, peripheral oedema; headache; muscle and joint pain; benign intracranial hypertension. Loss of glycaemic control in diabetics. |
| Drug Interactions | High doses of corticosteroid may inhibit growth-promoting effects of IGF1 DES. |
| Disclaimer | “Images displayed on the website are for representational purposes only which may differ from the actual purchased product. The company may change or alter the packaging design without notice.” |
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